Vumerity actress - Then, fax the Start Form to 1-855-474-3067. Prescriptions are only valid when received via fax. Your patient will be contacted by a pharmacy in the VUMERITY Pharmacy Network to arrange for delivery of the prescription. Please be sure to fill out all of the sections of the Start Form. Incomplete areas may delay the start of treatment.

 
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VUMERITY is a prescription medicine used to treat people with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults.Vumerity (diroximel fumarate) is a prescription capsule used to treat multiple sclerosis (MS) in adults. Learn about alternatives, side effects, dosage, and more.Bottom Line. Tips. Response/effectiveness. Interactions. 1. How it works. Vumerity (diroximel fumarate) is thought to work in relapsing forms of multiple sclerosis …While it is illegal for a woman to lose her job because of pregnancy, there are definitely some tasks that are harder to do while pregnant. This is especially the case for actresse...VUMERITY ® (diroximel fumarate) es un medicamento de venta con receta que se usa para tratar a personas con formas recurrentes de esclerosis múltiple (EM) en adultos, incluidos el síndrome clínicamente aislado, la enfermedad recurrente remitente y la enfermedad progresiva secundaria activa. Se desconoce si VUMERITY es seguro y efectivo en ...VUMERITY is a prescription medicine used to treat people with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease …Medically reviewed by Melissa Badowski, PharmD, MPH, FCCP — By Alex Brewer, PharmD, MBA on June 30, 2022. Learn about side effects, cost, and more for …Making the most of your treatment is an important goal as you continue on your journey with VUMERITY ® (diroximel fumarate). We have developed an app with tools that could help! myVUMERITY ™ is an app that can help you keep up with your. treatment routine: Set dosing reminders. Log each dose. Keep track of your upcoming lab appointments. The most common side effects of VUMERITY include: flushing, redness, itching, or rash. nausea, vomiting, diarrhea, stomach pain, or indigestion. Flushing and stomach problems are the most common reactions, especially at the start of therapy, and may decrease over time. Taking VUMERITY with food (avoid high-fat, high-calorie meal or snack) may ... VUMERITY may cause flushing (e.g., warmth, redness, itching, and/or burning sensation). In clinical trials of dimethyl fumarate (which has the same active metabolite as VUMERITY), 40% of dimethyl fumarate-treated patients experienced flushing. Flushing symptoms generally began soon after initiating dimethyl fumarate and usually improved or ...Among them are the most famous actresses who aren't just ruling the box office but are also style icons and powerful influencers in their own right. Zendaya, once a Disney darling, has morphed into a full-fledged star with Emmy-winning chops in Euphoria and a solid presence in big-ticket movies like Dune . The most common adverse reactions (incidence ≥10% and ≥2% more than placebo) for dimethyl fumarate (which has the same active metabolite as VUMERITY) were flushing, abdominal pain, diarrhea, and nausea. Gastrointestinal adverse reactions: Dimethyl fumarate caused GI events (e.g., nausea, vomiting, diarrhea, abdominal pain, and dyspepsia). Data from a matching-adjusted indirect comparison (MAIC) of ozanimod (Zeposia; Bristol Myers Squibb) and diroximel fumarate (Vumerity) in patients with relapsing-remitting multiple sclerosis (MS) indicated that the 2 disease-modifying therapies (DMTs) have comparable efficacy; however, ozanimod displayed a superior safety …Watch busy mom and VUMERITY ambassador Karen J. share why she chose VUMERITY, a pill for relapsing multiple sclerosis (MS). Everyone’s experience is …Data from a matching-adjusted indirect comparison (MAIC) of ozanimod (Zeposia; Bristol Myers Squibb) and diroximel fumarate (Vumerity) in patients with relapsing-remitting multiple sclerosis (MS) indicated that the two disease-modifying therapies (DMTs) have comparable efficacy; however, ozanimod displayed a superior safety profile, with …Start patients on VUMERITY by completing the Start Form, accessible via: • Once the Start Form is submitted, Biogen Support Serviceswill send the prescription to a specialty pharmacy to complete a Benefits Investigation on your behalf • Patients must sign Sections A and B in order for a Biogen Case Managerto proactively call them ...VUMERITY is a prescription medicine used to treat people with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in …Margot Robbie, the talented Australian actress, has not only made a name for herself in Hollywood with her impressive acting skills but has also become a style icon in the fashion ...Vumerity may also cause less stomach upset compared to Tecfidera, another medicine used for MS. In one study lasting 2 years, 73% of people taking Vumerity had no relapses after 2 years, compared to 54% taking a placebo (an inactive or “fake” pill). In addition, people were less likely to relapse (27% of people taking Vumerity had a relapse ...12 April 2022. The MS Trust is delighted that Vumerity (diroximel fumarate) has been approved by NICE (National Institute for Health and Care Excellence) for people with active relapsing remitting multiple sclerosis. NICE has recommended that Vumerity can be prescribed for people with relapsing remitting MS who are having relapses or have MRI ...Vumerity® Brand Name: Vumerity® (vue-mer'-i-tee) Chemical Name: diroximel fumarate (dye-ROX-i-mel FUE-ma-rate) Generic Available: No Description: Vumerity is a capsule taken twice a day by mouth. It is similar to another DMT, Tecfidera, but has a distinct chemical structure that has been shown to be better tolerated, with fewer reported ...Include warmth, redness, itching, and/or burning sensation. Guidance. Taking VUMERITY with food may reduce the incidence of flushing. Alternatively, taking non-enteric coated aspirin (up to a dose of 325 mg) 30 minutes prior to VUMERITY dosing may reduce the incidence or severity of flushing.Vumerity is available as capsules to be taken by mouth. The dose is 231 mg (one capsule) twice a day for the first seven days, after which it is increased to 462 mg (two capsules) twice a day. The dose may be reduced temporarily in patients experiencing side effects of flushing (reddening of the skin) or gastrointestinal (stomach and gut) problems. The most common side effects of VUMERITY include: flushing, redness, itching, or rash. nausea, vomiting, diarrhea, stomach pain, or indigestion. Flushing and stomach problems are the most common reactions, especially at the start of therapy, and may decrease over time. • Store VUMERITY at room temperature between 68°F to 77°F (20°C to 25°C). • Keep VUMERITY and all medicines out of the reach of children. General Information about the safe and effective use of VUMERITY . Medicines are sometimes prescribed for purposes other than those listed in this Patient Information. Do not useVumerity (diroximel fumarate) is an oral treatment for people with relapsing forms of MS. Learn about its uses, indications, and side effects. Remember, your healthcare provider should always be your primary source of information. Call us. 1-800-456-2255. 8:30 AM to 8 PM ET, Monday through Friday. Call a Biogen Support Coordinator from the privacy of your own home. Write to us. Biogen. 5000 Davis Drive, Vumerity (diroximel fumarate) is a prescription capsule used to treat multiple sclerosis (MS) in adults. Learn about alternatives, side effects, dosage, and more.Data from a matching-adjusted indirect comparison (MAIC) of ozanimod (Zeposia; Bristol Myers Squibb) and diroximel fumarate (Vumerity) in patients with relapsing-remitting multiple sclerosis (MS) indicated that the two disease-modifying therapies (DMTs) have comparable efficacy; however, ozanimod displayed a superior safety profile, with …Vumerity (diroximel fumarate) is an approved oral treatment for multiple sclerosis (MS) that helps to reduce relapse rates and slow the development of brain lesions. It also may delay disability ...If an empty suit that helped create this puss sack, reads this, it all comes back amigo. This commercial has a catchy jingle. Compared to this ad, 'Baby Shark', is ,'Citizen Cane'. If an empty suit that helped create this puss sack, reads this, it all comes back amigo.Who is the actress in the Kesimpta commercial? Medically reviewed by Carmen Pope, BPharm. Last updated on April 4, 2023. Official answer. by Drugs.com. …withholding VUMERITY in cases of serious infection until the infection has resolved. (5.3) • Lymphopenia: Obtain a CBC including lymphocyte count before initiating VUMERITY, after 6 months, and every 6 to 12 months thereafter. Consider interruption of VUMERITY if lymphocyte counts <0.5 × 109/L persist for more than six months. (5.4)Vumerity FDA Approval History. Last updated by Judith Stewart, BPharm on Jan 6, 2020.. FDA Approved: Yes (First approved October 29, 2019) Brand name: Vumerity Generic name: diroximel fumarate Dosage form: Delayed-Release Capsules Company: Biogen Inc. Treatment for: Multiple Sclerosis Vumerity (diroximel fumarate) is a novel … VUMERITY es un medicamento de venta con receta que se usa para tratar a personas con formas recurrentes de esclerosis múltiple (EM) en adultos, incluidos el síndrome clínicamente aislado, la enfermedad recurrente remitente y la enfermedad progresiva secundaria activa. si has tenido una reacción alérgica (como ronchas; urticaria; hinchazón ... VUMERITY is available as hard, delayed-release capsules containing 231 mg of diroximel fumarate. The capsules have a white cap and a white body, printed with “DRF 231 mg” in black ink on the ... 4 CONTRAINDICATIONS. VUMERITY is contraindicated in patients - With known hypersensitivity to diroximel fumarate, dimethyl …We would like to show you a description here but the site won’t allow us.VUMERITY is available as hard, delayed-release capsules containing 231 mg of diroximel fumarate. The capsules have a white cap and a white body, printed with “DRF 231 mg” in black ink on the ... 4 CONTRAINDICATIONS. VUMERITY is contraindicated in patients - With known hypersensitivity to diroximel fumarate, dimethyl …severe tiredness. loss of appetite. pain on the right side of your stomach. have dark or brown (tea color) urine. yellowing of your skin or the white part of your eyes. serious gastrointestinal problems, including bleeding, ulcers, blockage, and tears (perforation) of the stomach or intestines.Lääkevalmisteen kuvaus ja pakkauskoot. Vumerity 231 mg kovat enterokapselit ovat valkoisia, ja niissä on mustalla musteella merkintä ”DRF 231 mg”. Vumerity-kapseleita on saatavana 120 tai 360 (3 x 120) kapselin pakkauksissa. Kaikkia pakkauskokoja ei välttämättä ole myynnissä. The most common side effects of VUMERITY include: flushing, redness, itching, or rash. nausea, vomiting, diarrhea, stomach pain, or indigestion. Flushing and stomach problems are the most common reactions, especially at the start of therapy, and may decrease over time. Taking VUMERITY with food (avoid high-fat, high-calorie meal or snack) may ... Alyvia Alyn Lind is a young and talented actress who has made a name for herself in both television shows and movies. Despite her young age, she has already showcased her versatili...Other studies comparing Vumerity with Tecfidera, namely the EVOLVE-MS-2 trial (NCT03093324), further showed that Vumerity was generally safe and well tolerated, with patients having fewer ... Making the most of your treatment is an important goal as you continue on your journey with VUMERITY ® (diroximel fumarate). We have developed an app with tools that could help! myVUMERITY ™ is an app that can help you keep up with your. treatment routine: Set dosing reminders. Log each dose. Keep track of your upcoming lab appointments. Diroximel fumarate, sold under the brand name Vumerity, is a medication used for the treatment of relapsing forms of multiple sclerosis (MS). It acts as an immunosuppressant and anti-inflammatory drug. Its most common adverse effects are flushing and gastrointestinal problems.Getting into acting can be hard for anyone. Many families get their children into the profession at a young age, and many kids have to confront different hardships than what actors...The crypto exchange, which reportedly owes creditors $3 billion, initiated its third round of layoffs in less than a year as it struggles to adjust. Gemini Gemini is laying off 10%...Alyvia Alyn Lind is a young and talented actress who has made a name for herself in both television shows and movies. Despite her young age, she has already showcased her versatili...We would like to show you a description here but the site won’t allow us.Making the most of your treatment is an important goal as you continue on your journey with VUMERITY ® (diroximel fumarate). We have developed an app with tools that could help! myVUMERITY ™ is an app that can help you keep up with your. treatment routine: Set dosing reminders. Log each dose. Keep track of your upcoming lab appointments.74% of people taking VUMERITY pay $0 compared with only 18% of those taking a generic dimethyl fumarate1,b Biogen is committed to helping make treatment with VUMERITY affordable for your patients aBiogen Copay Program details and eligibility: • With the Biogen Copay Program, commercially insured patients may lower their out-of-pocket costsVumerity (diroximel fumarate) is a delayed-release capsule used to treat relapsing forms of the autoimmune disorder multiple sclerosis. It is thought to have an effect as early as 24 weeks after patients start taking it. MS is a condition in which a person’s own immune system mistakenly attacks the central nervous system (CNS), causing …What made Maureen, Philip and Laura consider switching to VUMERITY? Watch to find out. Everyone’s experience is different. Learn more about the potential ben...Vumerity should be used during pregnancy only if clearly needed and if the potential benefit justifies the potential risk to the foetus. Breast-feeding. It is unknown whether diroximel fumarate or its metabolites are excreted in human milk. A risk to the newborns/infants cannot be excluded. A decision must be made whether to discontinue breast ...Throughout the 2000s, the entertainment industry saw the emergence of some of the most skilled and versatile actresses and actors in the history of modern film. While many have thr...Making the most of your treatment is an important goal as you continue on your journey with VUMERITY ® (diroximel fumarate). We have developed an app with tools that could help! myVUMERITY ™ is an app that can help you keep up with your. treatment routine: Set dosing reminders. Log each dose. Keep track of your upcoming lab appointments.74% of people taking VUMERITY pay $0 compared with only 18% of those taking a generic dimethyl fumarate1,b Biogen is committed to helping make treatment with VUMERITY affordable for your patients aBiogen Copay Program details and eligibility: • With the Biogen Copay Program, commercially insured patients may lower their out-of-pocket costsSep 20, 2022 · Vumerity (diroximel fumarate) is a prescription capsule used to treat multiple sclerosis (MS) in adults. Learn about alternatives, side effects, dosage, and more. Becoming an actor at a young age can be an exciting and rewarding experience. However, navigating the entertainment industry as a kid actor can sometimes be challenging. The first ...The most common side effects of VUMERITY include: flushing, redness, itching, or rash. nausea, vomiting, diarrhea, stomach pain, or indigestion. Flushing and stomach problems are the most common reactions, especially at the start of therapy, and may decrease over time. Taking VUMERITY with food (avoid high-fat, high-calorie meal or snack) may ...The most common side effects of VUMERITY include: flushing, redness, itching, or rash. nausea, vomiting, diarrhea, stomach pain, or indigestion. Flushing and stomach problems are the most common reactions, especially at the start of therapy, and may decrease over time. Taking VUMERITY with food (avoid high-fat, high-calorie meal or snack) may ...Bottom Line. Tips. Response/effectiveness. Interactions. 1. How it works. Vumerity (diroximel fumarate) is thought to work in relapsing forms of multiple sclerosis (MS) by regulating the immune system to lower inflammation. It may also act as an antioxidant to help protect the brain and spinal cord in the central nervous system.Vumerity is a drug similar to Biogen’s Tecfidera (dimethyl fumarate), but it is reported to have fewer gastrointestinal side effects than Tecfidera. Vumerity did not have to undergo extensive clinical trials to demonstrate benefits for relapsing MS because once it is processed in the body, Vumerity converts to the same active ingredient as Tecfidera. 2VUMERITY is contraindicated in patients. With known hypersensitivity to diroximel fumarate, dimethyl fumarate, or to any of the excipients of VUMERITY. Reactions may include anaphylaxis and angioedema. MMF=metabolite monomethyl fumarate; MOA=mechanism of action; Nrf2=nuclear factor (erythroid-derived 2)-like 2. References: 1.VUMERITY contains diroximel fumarate. The chemical name of diroximel fumarate is. 2-Butenedioic acid (2E)-, 1-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl] 4-methyl ester, which has a molecular formula of C11H13NO6 and molecular weight of 255.22. Diroximel fumarate has the following structure:Making the most of your treatment is an important goal as you continue on your journey with VUMERITY ® (diroximel fumarate). We have developed an app with tools that could help! myVUMERITY ™ is an app that can help you keep up with your. treatment routine: Set dosing reminders. Log each dose. Keep track of your upcoming lab appointments.The most common adverse reactions (incidence ≥10% and ≥2% more than placebo) for dimethyl fumarate (which has the same active metabolite as VUMERITY) were flushing, abdominal pain, diarrhea, and nausea. Gastrointestinal adverse reactions: Dimethyl fumarate caused GI events (e.g., nausea, vomiting, diarrhea, abdominal pain, and dyspepsia).Diroximel fumarate (Vumerity®) for the treatment of adult patients with relapsing-remitting multiple sclerosis (RRMS) (February 2022) Funding decision: Recommended. Medicinal forms. There can be variation in the licensing of different medicines containing the …• Store VUMERITY at room temperature between 68°F to 77°F (20°C to 25°C). • Keep VUMERITY and all medicines out of the reach of children. General Information about the safe and effective use of VUMERITY . Medicines are sometimes prescribed for purposes other than those listed in this Patient Information. Do not useThe most common adverse reactions (incidence ≥10% and ≥2% more than placebo) for dimethyl fumarate (which has the same active metabolite as VUMERITY) were flushing, abdominal pain, diarrhea, and nausea. Gastrointestinal adverse reactions: Dimethyl fumarate caused GI events (e.g., nausea, vomiting, diarrhea, abdominal pain, and dyspepsia).We would like to show you a description here but the site won’t allow us.Vumerity is a twice a day oral medication for patients with multiple sclerosis. The active ingredient of Vumerity is diroximel fumarate, which is rapidly converted to monomethyl fumarate in the body. Similarly dimethyl fumarate (Tecfidera) is also converted to monomethyl fumarate. Therefore, Vumerity would be expected to the same benefits as ...by Steve Bryson, PhD November 21, 2023. Nearly two years of treatment with Vumerity (diroximel fumarate) significantly reduced relapse rates by more than 80% in people with relapsing-remitting...May 21, 2023 · Vumerity can cause certain side effects, some of which are more common than others. These side effects may be temporary, lasting a few days to weeks. However, if the side effects last longer than ... 12 April 2022. The MS Trust is delighted that Vumerity (diroximel fumarate) has been approved by NICE (National Institute for Health and Care Excellence) for people with active relapsing remitting multiple sclerosis. NICE has recommended that Vumerity can be prescribed for people with relapsing remitting MS who are having relapses or have MRI ...VUMERITY is a prescription medicine used to treat people with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease in adults. It is not known if VUMERITY is safe and effective in children.VUMERITY Offers the Efficacy Demonstrated by dimethyl fumarate Across 2 Pivotal Trials. The efficacy of VUMERITY is based upon bioavailability studies in patients with relapsing forms of multiple sclerosis and healthy subjects comparing oral dimethyl fumarate (DMF) delayed-release capsules to VUMERITY delayed-release capsules.withholding VUMERITY in cases of serious infection until the infection has resolved. (5.3) •Lymphopenia: Obtain a CBC including lymphocyte count before initiating VUMERITY, after 6 months, and every 6 to 12 months thereafter. Consider interruption of VUMERITY if lymphocyte counts <0.5 × 109/L persist for more than six months. (5.4)

Vumerity (diroximel fumarate) commonly causes stomach issues, such as nausea, vomiting, diarrhea, or stomach pain, especially when you first start the medication. If this becomes bothersome, over-the-counter medications, like antacids, might help. Ask you provider or pharmacist for recommendations on what you can take.. Credentia skills

vumerity actress

Lääkevalmisteen kuvaus ja pakkauskoot. Vumerity 231 mg kovat enterokapselit ovat valkoisia, ja niissä on mustalla musteella merkintä ”DRF 231 mg”. Vumerity-kapseleita on saatavana 120 tai 360 (3 x 120) kapselin pakkauksissa. Kaikkia pakkauskokoja ei välttämättä ole myynnissä.Actress Anya Taylor-Joy kicked 2024 off with a bang while posing topless in a traditional corset.The pic came ahead of her red carpet appearance for Dune: Part Two in New York City, giving fans a ... At Biogen, our goal is for everyone to get the support they need. Biogen Support Services has financial and insurance assistance options that can help you manage your VUMERITY® (diroximel fumarate) cost, depending on your individual needs. If you have any questions, call 1-800-456-2255 Monday-Friday from 8:30 AM to 8 PM ET. The most common side effects of VUMERITY include: flushing, redness, itching, or rash. nausea, vomiting, diarrhea, stomach pain, or indigestion. Flushing and stomach problems are the most common reactions, especially at the start of therapy, and may decrease over time. Check out the most beautiful Hollywood actresses of all time. This includes most beautiful actresses of all time like Marilyn Monroe and others like Emma Watson, Penélope Cruz, Megan Fox, Audrey Hepburn, Jennifer Lawrence, Kate Winslet, Nina Dobrev, Rachel McAdams, Anna Hathway, Angelina Jolie, Sophie turner and many m.withholding VUMERITY in cases of serious infection until the infection has resolved. (5.3) •Lymphopenia: Obtain a CBC including lymphocyte count before initiating VUMERITY, after 6 months, and every 6 to 12 months thereafter. Consider interruption of VUMERITY if lymphocyte counts <0.5 × 109/L persist for more than six months. (5.4)Becoming an actor at a young age can be an exciting and rewarding experience. However, navigating the entertainment industry as a kid actor can sometimes be challenging. The first ...flushing, redness, itching, or rash. nausea, vomiting, diarrhea, stomach pain, or indigestion. Flushing and stomach problems are the most common reactions, especially at the start of therapy, and may decrease over time. Taking VUMERITY with food (avoid high-fat, high-calorie meal or snack) may help reduce flushing. VUMERITY con alimentos (evita comidas o meriendas con alto contenido de grasas y calorías) podría ayudar a reducir el enrojecimiento. Llama a tu médico si tienes alguno de estos síntomas y te molestan o no desaparecen. Pregúntale a tu médico si tomar aspirina antes de tomar VUMERITY podría reducir el enrojecimiento. Alice Eve. The Actress: The daughter of British actor Trever Eve, Alice had appeared in minor roles in half-baked tosh such as Sex And The City 2 and Harrison Ford clunker Crossing Over , before ... Pringles. 3. Gigi Hadid. Actress | Ocean's Eight. Jelena Noura "Gigi" Hadid is an American model. She was signed to IMG Models in 2013. In November 2014, Hadid made her debut in the Top 50 Models ranking at Models. In 2016, she was named International Model of the Year by the British Fashion Council. Gigi Hadid was born and raised in Los ... Pronunciation of vumerity with 2 audio pronunciations, 3 sentences and more for vumerity. ... Celebrities who survived COVID 19-Private. 22 World's Best Airport-Private. 10 Popular quizzes How good are you in English? 15 Questions. 6851 Attempts. Guess The Singers By Their Songs ...In a new profile about Vayntrub published in the New York Times on Thursday, the actress reflected on the highs and lows of portraying Lily on a national platform. After appearing in her first ...Making the most of your treatment is an important goal as you continue on your journey with VUMERITY ® (diroximel fumarate). We have developed an app with tools that could help! myVUMERITY ™ is an app that can help you keep up with your. treatment routine: Set dosing reminders. Log each dose. Keep track of your upcoming lab appointments.VUMERITY may cause flushing (e.g., warmth, redness, itching, and/or burning sensation). In clinical trials of dimethyl fumarate (which has the same active metabolite as VUMERITY), 40% of dimethyl fumarate-treated patients experienced flushing. Flushing symptoms generally began soon after initiating dimethyl fumarate and usually improved or ...Vumerity (diroximel fumarate) is a delayed-release capsule used to treat relapsing forms of the autoimmune disorder multiple sclerosis (MS).. Vumerity contains diroximel fumarate. Diroximel fumarate is rapidly converted in the body to monomethyl fumarate (MMF), which is the same active metabolite Tecfidera (dimethyl fumarate) has.. …Apr 15, 2024 · Take VUMERITY exactly as your doctor tells you to take it. The recommended starting dose on days 1 to 7 is one capsule by mouth 2 times a day. After 7 days, the recommended dose is 2 capsules by mouth 2 times a day. If taken with food, avoid taking VUMERITY with a high-fat, high-calorie meal or snack. VUMERITY at the first sign or symptom suggestive of PML. (5.2) • Herpes Zoster and Other Serious Opportunistic Infections: Consider withholding VUMERITY in cases of serious infection until the infection 5.3) • Lymphopenia: Obtain a CBC including lymphocyte count before initiating VUMERITY, after 6 months, and every 6 to 12 months thereafter..

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